|A Canary's Eye View Metabolic Basis|
|My Genovations DetoxiGenomic Profile - Phase I
Enzymes, known collectively as the cytochrome P-450 system, use oxygen to modify toxic compounds, drugs, or steroid hormones.
General Therapies to Improve Detoxification:
Foods that generally improve Phase I detoxification and as well improve the efficiency of Phase II conjugation are generally recommended for individuals with CYP SNPs. These include most vegetables and fruits, but especially
Use of H2 blockers (e.g. Cimetidine) should be avoided as these bind to the heme-containing reactive site of all CYPs inhibiting binding to toxins.
Polymorphisms detected in 2 CYP genes:
CYP1A1 (multiple SNP locations evaluated for this gene) - upregulated
CYP1B1 (multiple SNP locations evaluated for this gene) - upregulated
CYP genes tested but no polymorphism detected:
Last updated 11 December 2007