|A Canary's Eye View Metabolic Basis|
|Interpretation of Liver Detox Profile
Caffeine Clearance - within range, but in relation to Phase II processes, is out of balance. Specifically looking at the Phase I / glycination ratio, I am a "pathological detoxifier." My P450 enzymes make their toxic products too fast for my glycination to handle.
Sulfur Metabolism: for details see Defect(s) in my Sulfur Metabolism
Glucuronidation low (just within reference range): this surprised me too, because I had been taking Calcium D-Glucarate to support this pathway. So I increased the dose, from 500 mg daily (2 capsules) to the maximum suggested dose of 2250 mg. Results were dramatic: I can now tolerate a lot more exposures to chemicals that would have made me very sick before. Glucuronidation is a slow pathway; often I'll start to feel bad on exposure, but if I get away from it and into good, fresh air, I can recover without a full liver attack. High doses of this loosen my bowels, but I've been able to balance that with foods that tend to constipate me.
Last updated 21 March 2008